Umberto Veronesi
The great evil strikes at any age. And increase in cases among young adults. But by preventing the battle can be won. Starting early to make checks. Moving away from smoke and grease. And vaccination against HPV. The famous doctor explains how to save the life .
A school was more about science, but I also really liked the Italian. With great interest per le regole della linguistica, e con la curiosità di rintracciare le radici delle parole, che a volte sembrano montate secondo le modalità di un semplicissimo puzzle. Prevenzione, ad esempio, è l'atto, l'effetto del pre-venire. E prevenire ha due significati: precedere qualcuno o qualcosa arrivando prima; e provvedere in anticipo, cercando di evitare qualcosa. L'Associazione italiana per la ricerca sul cancro dedica la sua giornata dell'11 maggio all'urgenza di anticipare i tempi della prevenzione, che colpisce ormai molto anche i giovani adulti. Per loro, per le giovani donne che si ammalano di tumore del seno o per le adolescenti che devono scegliere se vaccinarsi contro il tumore della cervice, mi sembra particolarmente urgente e importante emphasize that to get "before" of the tumor, avoided, thanks to healthy lifestyles, or hit with early diagnosis, it means to work on time. Fortunately, except for rare cases of fulminant cancer, time is in favor of prevention, because cancer usually takes a long time to develop. I have called "the long night of cancer," with the intent to draw attention to the fact that this very long incubation puts us in a position to do prevention. Even for the giovani.In substance, tumor proliferation is a multistep process that can last a lifetime. The cell growth may, initially, not to exceed what we call the "immune surveillance": the defenses of our body identify and eliminate cancer cells. They are little miracles that continue to be silent in our body, of which we are not aware of which no trace remains. What went well, in fact. In other cases, the cellular DNA, nicked by carcinogens, undergoes a change that is neither fixed nor blocked, and cells respond to proliferative stimuli begin to multiply excessively. It is a process that lasts for years: five, ten, twenty, even more. What all this time?
is the question that cancer research is trying to answer. The main steps are six. One, oncogene activation. Two, no activation of the gene deletion deputy to the oncogene. Three, the beginning of the multiplication of cancer cells. Four, the growth of new blood vessels feeding the tumor to Members. Five, the disappearance of the normal mechanism of cell death program that balance: in essence, cancer cells are eternizzano, and decades it has been discovered in the laboratory on cultured cells. Finally, the sixth step, the last one: in the progression of the cancer cells have acquired their typical biological characteristics, including invasive trend, the ability to establish settlements at a distance. So here is the metastasis.
is the sequence of a bad movie, a movie that puts the shivers. But not a script is required, it is not inevitable. Just the "long night of cancer," that is the long latency period, allows us to play on time to beat the disease. We are moving towards the possibility of ever earlier diagnosis, and probably within ten or twenty years we will pass over a detector that can detect tumors in the body of a single cell, which will be easy to destroy. Meanwhile (and this is where drugs come into play more targeted and more effective) we are trying to identify more accurately the boundary between the reversible stage of tumor and the point of no return in the path that leads to healthy cell or the aggregate of cells to turn into a mass of cellule maligne in progressivo accrescimento. Ma giocare sul tempo ha anche un'altra valenza, importantissima. Significa, in buona sostanza, che la prevenzione (sia come stili di vita, sia come semplici e facili controlli di routine per fare diagnosi precoce) va fatta subito, fin da giovani. Bisogna approfittare della "lunga notte del tumore" per batterlo sul tempo, e far sì che non si manifesti. Sappiamo tutti che i giovani si sentono immortali, non vogliono sentir parlare di malattia e di morte, e lo definiscono "gufare", con un parola di gergo giovanile molto espressiva.
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